Similar to what we found, a cross-sectional study including only subjects with T1D reported no association between skin AGEs measured with the SCOUT DS spectrometer and serum CTX, tartrate-resistant acid phosphatase 5b (TRACP5b), bone alkaline phosphatase, P1NP, and sclerostin, after adjustment for eGFR.48 This evidence concerns the gene CYP27A1 and type 1 diabetes mellitus.