TLR4 and osteoporosis: In the MEDLINE database, we searched the eligible studies by using the following keywords: ((((((((“Toll-Like Receptor 4”[Mesh]) OR (TLR4)) OR (TLR-4)) OR (Toll Like Receptor 4)) OR (Toll-4 Receptor)) OR (Toll 4 Receptor)) OR (TLR4 Receptor)) OR (Receptor, TLR4)) AND ((((“Osteoporosis”[Mesh]) OR (Osteoporoses)) OR (Bone Loss)) OR (Bone Losses)).