S100A9 and atherosclerosis: Kawakami et al.63further validated the influence of macrophage‐derived S100A9 on atherosclerosis and discovered that control mice had S100A9‐positive macrophages in plaques, while almost none were found in plaques of siS100A9 mice, and the expression of inflammatory factors and vascular calcification markers were significantly reduced in splenic macrophages; in addition, colocalization of S100A9 with RAGE was observed in plaques.