Furthermore, the increase in IL‐10 mRNA expression throughout the course of treatment, this elevation in IL‐10 has also been observed in a murine model of atherosclerosis that received valsartan (10 mg/kg) for 8 weeks43 and in a rat colitis model with valsartan (160 mg/L) treatment for 1 month.44 Here, IL10 is linked to atherosclerosis.