By analyzing the pancreas and spleens 6 weeks after cancer cell injection, we found the incidence of spleen metastasis was 83.33% (5/6) in the LINC00909-OE group and was 16.67% (1/6) of mice in the control group, indicating that LINC00909 accelerated PDAC metastasis in vivo (Fig. 7E-H). Here, ZNF407-AS1 is linked to cancer.