TMEM120B and breast carcinoma: Subsequent western blotting assay also revealed no visible alteration by overexpressing TMEM120B-FL and TMEM120B-NLS-mutant in SK-BR-3 cells, respectively (Additional file 3: Fig. S8F).Third, TMEM120B promoted breast cancer cells by binding with MYH9 which was previously reported as a cytosolic protein [33, 34].Therefore, from our current results, cytosolic TMEM120B may serve as an oncogenic protein rather than nuclear one, however, the function of TMEM120B should be further investigated in the future.