Subsequent immunohistochemical (IHC) staining of 20 cases of lung cancer, 29 cases of breast cancer, 21 cases of gastric carcinoma, 24 cases of colon cancer, 20 cases of ovarian cancer, and paired normal tissues suggested that TMEM120B expression was elevated in all malignant cancerous tissues compared with that in normal tissues (Fig. 1B:a-j and Table 1). The gene discussed is TMEM120B; the disease is malignant colon neoplasm.