Consistently, this conclusion was also confirmed by an immunofluorescence assay, which visibly exhibited the reduced nuclear translocation of β-catenin after silencing SERPINB12 expression (Fig. 4E-F) and the increased nuclear translocation of β-catenin after SERPINB12 overexpression (Supplementary Fig. 4B) in NSCLC cells, as revealed by immunofluorescence (IF). This evidence concerns the gene SERPINB12 and non-small cell lung carcinoma.