Moreover, 9/16 rhesus CRCs exhibited KRAS mutations including p.G12D (4/16 rhesus CRCs, most frequently affected KRAS codon and most frequent KRAS mutation in human cancers), p.G12S, p.G13D, p.A59T, p.Q61R, p.R68W, and p.A146T. Here, KRAS is linked to cancer.