Somatic mutations called in rhesus CRC showed remarkable overlap with their human counterparts (Additional file 2: File S1), affecting the Wnt pathway (APC, AMER1), MAPKKK pathway (KRAS, NF1), AKT pathway (AKT1, PTEN), kinase pathway receptors (ALK, EGFR), epigenetic regulators (ARID1A, EP300), DNA repair (ATM, ATR), and cell adhesion (CDH1, PTPRT). This evidence concerns the gene AKT1 and colorectal carcinoma.