Alzheimer’s disease (AD), the primary cause of dementia accounting for 60% to 80% of cases [1–3], is a progressive neurological disorder characterized by the presence of abnormal protein deposits in the brain such as beta-amyloid (Aβ) plaques and neurofibrillary tangles (NFTs) composed of tau protein [4–7]. The gene discussed is MAPT; the disease is Alzheimer disease.