THPO and Thrombocytopenia: The possible mechanisms of SARS-CoV-2 infection-induced thrombocytopenia include direct hematopoietic stem or progenitor cell invasion and lung injury mediated by autoantibodies and immune complexes, defective bone marrow microenvironment, decreased thrombopoietin production, and inhibition of megakaryocytopoiesis by cellular immunity and cytokine storm [45, 46].