Low SUA concentration could reflect weakness and malnutrition, so the present analysis excluded patients who had died within 6 months of follow-up, and adjusted for indicators of nutritional status (e.g., BMI, total cholesterol, hemoglobin, and serum albumin) and comorbidities (hypertension, diabetes, CV disease, CCI) to make the results more reliable. The gene discussed is ALB; the disease is malnutrition.