KMT2A and acute myeloid leukemia: The IC50 values for haematological cancers ranged from 0.96 μM for the Cas9 Flt3-ITD MLL-AF4 AML cell line to 41.83 μM for the Jurkat T-acute lymphoblastic leukaemia cell line; for solid cancers, they ranged from 2.57 μM for the Caco-2 colon cancer cell line to 42.04 μM for the SCC-9 oral squamous cell cancer cell line (Table S1).