AML伴BCR::ABL1患者脾脏多正常或轻中度肿大,CML-MBC患者多表现为脾脏重度肿大[15]。7例患者中仅1例伴重度脾大,同时综合其他鉴别诊断要点(包括外周血、骨髓细胞形态、既往病史、分子生物学及遗传学特征),仍考虑患者诊断AML伴BCR::ABL1。. The gene discussed is BCR; the disease is acute myeloid leukemia.