VSIR and familial pancreatic carcinoma: In multivariate analysis, high RNA expression of VISTA was positively associated with small intestine cancer [odds ratio (OR) 5.87, 95% confidence interval (CI) 1.48-29.3, P = 0.017], stomach cancer (OR 3.05, 95% CI 1.23-7.61, P = 0.015), and pancreatic cancer (OR 1.95, 95% CI 1.00-3.77, P = 0.048), and negatively associated with breast cancer (OR 0.32, 95% CI 0.12-0.75, P = 0.013) (Table 1).