MRC1 and infarction: Furthermore, the importance of macrophages in MI treatment research is highlighted, as the balance between pro‐inflammatory (M1) and anti‐inflammatory (M2) macrophages in the infarct area plays an important role in infarct expansion and adverse cardiac remodeling.[40, 41] As a result of co‐staining for CD86, an M1 specific marker, and CD206, an M2 specific marker, it was confirmed that pdHA_t, unlike control and pHA_t, significantly improved the distribution of CD206 cells while reducing the distribution of CD86 cells at the infarction site (Figure S12, Supporting Information).