MAOB and amyloidosis: Nevertheless, an early increase in MAO-B has been reported in the thalamus of PS2APP mice at 5, 13, and 19 months and in the hippocampus at 14 and 19 months compared with that in wild-type mice by using [18F]F-DED [3], and in 6-month-old APPswe mice preceding amyloid plaque deposition using [11C]AZD2184 [66] using [11C]DED.