To explore the association between ATM score and tumor categorization, we compiled genes related to cold and hot tumors from the study by Dong Wang et al., encompassing 12 hot tumor-related genes (CXCL9, CXCL10, CXCL11, CXCR3, CD3, CD4, CD8a, CD8b, CD274, PDCD1, CXCR4, and CCL5), and 3 cold tumor-related genes (CXCL1, CXCL2, and CCL20) [53]. This evidence concerns the gene CXCR4 and neoplasm.