Indeed, concentrations of CXCL10 were significantly higher in the first 48 hours of intubation in both BAL fluid and plasma from patients with COVID-19, relative to all other groups (q < 0.05, Mann-Whitney), and CXCL10 protein levels, alone, on initial BAL (AUROC = 0.88, P = 1.8 × 10–5) and plasma draw (AUROC = 0.83, P = 1.1 × 10–5) were highly predictive of COVID-19 status (Supplemental Figure 2, G and H). The gene discussed is CXCL10; the disease is COVID-19.