ALKBH5 and hepatocellular carcinoma: Among them, TTI1 has the highest correlation with ALKBH5 (r ═ 0.46), followed by ADNP (r ═ 0.39) and ACIN1 (r ═ 0.36), therefore, we identified TTI1 as the key downstream gene of ALKBH5. TTI1 expression was shown to be considerably greater in HCC tumors than in normal tissues (Figure 7D).