Finally, the subgroup analyses were conducted according to different TAMs markers (CD68, CD163 and CD204) and histologic locations (TI+TS, TI, and TS) to assess the effect of TAMs on the prognosis of ESCC, including OS and DFS, which made our pooled analysis more informative and persuasive. The gene discussed is CD68; the disease is esophageal squamous cell carcinoma.