In summary, there is no clear evidence that AMH is involved in testicular descent: although clinical observations in patients with PMDS seem to suggest a role for AMH in the INSL3-mediated swelling of the gubernaculum, experimental evidence could not be obtained from rodent models, probably due to species differences as regard the physiology of testicular descent between rodents and humans (71). The gene discussed is AMH; the disease is persistent Mullerian duct syndrome.