C1R and systemic lupus erythematosus: Recent studies have described several novel genes associated with SLE following WES analysis in an Asian population, such as the decreased expression of cell division cycle 27 (CDC27) in patients (Shang et al., 2022), and novel variants in genes encoding for complement receptor 2 (CR2) (Tang and Luo, 2022), C1R (Demirkaya et al., 2017), NRAS, TNFAIP3 and PIK3CD (Li et al., 2020), WNT16 and ERVW-1 (Chen et al., 2022), ACP5 and SAMHD1 (Hong et al., 2022).