SNCA and Parkinson disease: The build-up of aberrant, fibrillary, intraneuronal accumulations of misfolded α-synuclein protein, which are known as Lewy bodies (presence of Lewy pathology) along with the degeneration and degradation of the dopaminergic neurons in the nigral striatal pathway, constitutes one of the major hallmarks of Parkinson’s neuropathology [2,3].