Additionally, Triglyceride levels were significantly increased in the psoriasis group (WMD = 5.22; 95% CI = 2.23, 8.21, <i>P</i> = 0.001).<h4>Conclusion</h4>Our results revealed that TNF-alpha inhibitors might temporarily increase high-density lipoprotein levels in patients with psoriasis. The gene discussed is TNF; the disease is psoriasis.