Although a completely different biomarker panel (Olink Proseek Multiplex CVD I96 × 96) was used in our prior hypertensive heart disease study (11), most of the biomarkers that correlated with ECV and left ventricular hypertrophy were associated with inflammatory pathways such as interleukin-18 (IL-18), interleukin-6 (IL-6), and tumor necrosis factor (TNF). The gene discussed is TNF; the disease is left ventricular hypertrophy.