Upregulation of a series of coordinated lipogenic enzymes, such as ATP-citrate lyase (ACLY), acetyl-CoA carboxylase (ACC), fatty acid synthase (FASN), and stearoyl-CoA desaturase-1 (SCD1), endows potent lipogenic capacity on tumor cells, and changes in these enzymes have been found at different stages of tumorigenesis and tumor progression [46, 47]. This evidence concerns the gene ACLY and neoplasm.