It is currently believed that two distinct populations of LDs coexist within benign and tumor cells, termed growing LDs (smaller LDs resulting from ER budding with the catalyzation of DGAT1) and expanding LDs (larger LDs resulting from the in situ enzymatic activity of DGAT2 that translocate to the LDs from the ER), respectively [73, 85, 86]. This evidence concerns the gene DGAT1 and neoplasm.