DGAT1 and neoplasm: DGAT1 is most highly expressed in the small intestine, adrenal gland, rectum and duodenum tissue, and its activity is essential for the absorption of dietary fat through acylation of acylglycerols in the intestine, which is accountable for the esterification of exogenous fatty acids (FAs) to glycerol and is required for the synthesis of fat for storage in almost all human somatic cells and tumor cells [27].