TP53 and melanoma: DGAT1 is frequently upregulated in melanoma, and overexpression of DGAT1 has been shown to cooperate with oncogenic B-Raf proto-oncogene, serine/threonine kinase (BRAF) or neuroblastoma RAS viral oncogene homolog (NRAS) in p53 mutant melanocytes, resulting in more rapid melanoma formation.