CD86 and Alzheimer disease: As shown in Fig. 9A and B, the mRNA level of Arg-1 in AD-MSCs with LPS were significantly higher than that in LPS group (P < 0.01), and the mRNA level of CD86 in AD-MSCs with LPS with LPS were remarkably lower than that in LPS group (P < 0.01), indicating that AD-MSCs are capable of promoting BV2 cell polarization from M1 to M2.