The 10 most significantly enriched signaling pathways were ‘arrhythmogenic right ventricular cardiomyopathy’ (FDR: 0.057189133), ‘hypertrophic cardiomyopathy’ (FDR: 0.063430675), ‘cardiac muscle contraction’ (FDR: 0.21866133), ‘GABAergic synapse’ (FDR: 0.21866133), ‘dilated cardiomyopathy’ (FDR: 0.21866133), ‘serotonergic synapse’ (FDR: 0.334112021), ‘GnRH secretion’ (FDR: 0.334112021), ‘renin secretion’ (FDR: 0.395775367), ‘oxytocin signaling pathway’ (FDR: 0.525036286), and ‘adrenergic signaling in cardiomyocytes’ (FDR: 0.525036286). This evidence concerns the gene REN and dilated cardiomyopathy.