CDK4 and neoplasm: As a result, in addition to GAMs population subdivided into low-, medium- and high-SORL1 expressing cells, we defined the populations of tumor cells (clusters 0, 7, 8, 9, 15, expressing CDK4, MT1X, ATRX, CCND2, MDM2, SOX4, CD9, CDK6, S100B), lymphocytes (clusters 5, 17, 19; GZMK, CD3E, PTPRC, CCL5, IL32, CD69, CD52), smooth muscle cells (cluster 11; ACTA2, TAGLN), endothelial cells (cluster 14; EDN1 PECAM1 ANGPT2), oligodendrocytes (cluster 12, MBP, CNP) and other cells whose classification was dubious (clusters 4, 18, 20).