Intrigued by the fact that not all Iba1+ cells in patients specimens stained positive for SorLA, we analyzed the proportions of AIF1 (encoding for Iba1) expressing cells that also express SORL1 in several scRNA-seq datasets from GBM samples (Data Ref.: Sankowski et al, 2019; Abdelfattah et al, 2022; Chen et al, 2021; Neftel et al, 2019; Pombo Antunes et al, 2021; Wang et al, 2022b). This evidence concerns the gene SORL1 and glioblastoma.