SORL1 and central nervous system cancer: This was not due to the overall increase in neutrophil amounts in the circulating blood of SorLA-KO mice, as the numbers of circulating neutrophils, as well as of erythrocytes, monocytes, lymphocytes, basophils, and eosinophils, were comparable in glioma-bearing WT and SorLA-KO mice (Appendix Fig. S9).