CD8A and neoplasm: Dysregulation of Fe metabolism in Fth-deleted Treg cells was associated with better control of tumor progression (Fig. 8H), consistent with a relative reduction of tumor-infiltrating Treg cells (Fig. 8I) and a more pronounced activation and/or infiltration of activated T effector cells (Fig. 8J), including CD8+IFNγ+ TC cells (Fig. EV5F).