Interestingly, our research indicated a positive correlation between MCM4 expression and tumor purity in cancers such as GBM, LGG, CESC, BRCA, ESCA, STES, SARC, KIRP, STAD, UCEC, HNSC, LUSC, TGCT, PCPG, SKCM, and ACC, while THYM and READ showed a negative correlation (Fig. S5F). This evidence concerns the gene MCM4 and cancer.