MCM4 and cancer: Finally, our study revealed a positive correlation between MCM4 expression and LOH in cancers such as GBM, SARC, KIRP, GBMLGG, LAML, BRCA, LGG, LUAD, ESCA, KIPAN, PRAD, LIHC, PAAD, UCEC, KIRC, LUSC, OV, UVM, BLCA, and CHOL, while THCA showed a negative correlation (Fig. S5H).