MCM4 and adrenal cortex carcinoma: Similarly, high MCM4 expression was correlated with poor DFS prognosis in ACC (P = 0.0018), KICH (P = 0.044), LGG (P = 0.0031), LUAD (P = 0.047), MESO (P = 0.03), PAAD (P = 0.0083), and THCA (P = 0.027), as illustrated in Fig. 8B. Conversely, low expression of MCM4 was associated with unfavorable DFS prognosis in COAD (P = 0.019).