Interestingly, our research indicated a positive correlation between MCM4 expression and tumor purity in cancers such as GBM, LGG, CESC, BRCA, ESCA, STES, SARC, KIRP, STAD, UCEC, HNSC, LUSC, TGCT, PCPG, SKCM, and ACC, while THYM and READ showed a negative correlation (Fig. S5F). Here, MCM4 is linked to glioblastoma.