Specifically, we observed that high MCM4 expression levels correlated with increased HRD in GBM, LUAD, GBMLGG, LGG, KIPAN, KIRP, BRCA, SARC, PRAD, UCEC, LIHC, PAAD, HNSC, LUSC, BLCA, OV, ACC, and KICH (Fig. S5A). The gene discussed is MCM4; the disease is glioblastoma.