To affirm the fact that YBX1 is upregulated in AML‐sEVs, western blot for YBX1 was performed with various AML (MV4‐11 cells and their sEVs, sEVs from blood plasma of fifteen paediatric AML patients) and non‐AML samples (K562, HeLa, HUVEC cells and their sEVs, sEVs isolated from blood plasma of fifteen paediatric healthy controls) (Figure 4a). Here, YBX1 is linked to acute myeloid leukemia.