Western blot analysis revealed the presence of ENPP1 in exosomes derived from various human tumor cells lines, which included lung cancer A549, melanoma A375, oral cancer CAL27, colorectal cancer SW480, cervical cancer HeLa, breast cancer MDA‐MB‐231, and glioma U251 (Figure 1C). The gene discussed is ENPP1; the disease is lip and oral cavity carcinoma.