ENPP1 and neoplasm: To evade immune surveillance, tumor exosomal ENPP1 can effectively hydrolyze extracellular 2′3′‐cGAMP or 2′3′‐cGAMP bound to LL‐37 (an effective transporter of 2′3′‐cGAMP) to inhibit cGAS‐STING pathway in immune cells.