CGAS and neoplasm: Disparity B reflects the difference in ISRE reporter activity of THP1‐Lucia ISG cells treated with a combination of exosomes and 2′3′‐cGAMP with or without STF‐1623, which indicates the inhibitory effect of tumor exosomal ENPP1 on the cGAS‐STING pathway through hydrolysis of 2′3′‐cGAMP (Figure 2C).