Indeed, unlike free 2′3′‐cGAMP (Figure 2C), LL‐37‐2′3′‐cGAMP‐induced ISRE reporter activity was not affected by tumor‐derived exosomes concentration in presence STF‐1623 (Figure 3B), which suggests further that tumor‐derived exosomes did not assist LL‐37‐2′3′‐cGAMP to activate cGAS‐STING pathway. The gene discussed is CGAS; the disease is neoplasm.