RHEB and cancer: For instance, FOXP1 expression in breast cancer cells negatively regulates tumor‐infiltrating lymphocyte migration by inhibiting lymphoid chemokine expression.[25] Accordingly, enhanced cancer‐cell‐intrinsic characteristics, such as protein translation (EIF3B, EIF2B4, EIF2B5), DNA repair (ERCC2, NME1, and POLR1C), oxidative phosphorylation (NDUFA1, NDUFA2, and NDUFA4), and mTOR signaling (RHEB, LAMTOR2, and MTOR) were observed in TLS‐low group.