Abstinence > 2 mo, jaundice > 3 mo, other liver diseases, malignancies, steroid or pentoxifylline use in last 6 weeks, AST > 500, ALT > 300, creatinine > 500mmol/L, RRT, inotropes, GI bleed, untreated sepsis, cerebral hemorrhage, extensive retinal hemorrhage, acute myocardial infarction, arrhythmia, pregnancy, and lactating women. The gene discussed is GPT; the disease is myocardial infarction.