B5 displayed expression of genes related to germinal-center B cells, including aicda (AID), mki67, top2a, stmn1a, bach2b, bcl6aa, bcl6ab, cd81a, cd9a, irf8, lmo2, pclaf, and nfkb2, which exhibited a notable increase following virus infection (Figure 6A–C). This evidence concerns the gene IRF8 and viral infectious disease.