ASZ1 and infection: Further, we predicted the phosphorylated residues in ORF3 protein sequences as reportshave revealed the importance of post-translational modifications (PTMs) in numerous processes (protein folding, signal transduction,apoptosis, etc) [84], as well as in the infection cycle of intracellular pathogens[85,86], like Alphaviruses [87,88] and Flaviviruses [89,90,91].