TEX46 and neoplasm: To reveal the overall pattern of T cell phenotypes across the TdLN and tumor, we identified two highly correlated modules consisting of genes associated with a stemness module in the TdLN and an exhaustion module in the tumor (Figures 3G–3H) consistent with prior reports.22,25 These data confirm that TSTEM and TEX sit at opposite ends of a T cell differentiation spectrum.