GLRX and necrotizing enterocolitis: Furthermore, necrosis in the intestinal epithelium, as evidenced by SYTOX Green staining, a necrosis marker that is used to detect cell death in the ileal epithelium based on its binding property to cellular nucleic acids present only in dead cells, was enhanced in NEC but considerably decreased by Grx1−/− (Figures 5E and 5F).