Amongst other DC subtypes, there was no observed difference in the proportion of cDC1s between AML and WT, but significant decreases in pDCs and CCR7+ DCs, and increase in monocyte-like DCs were also observed in AML splenocytes, although to a lesser extent than the shift in Tbet-/+ cDC2s. This evidence concerns the gene TBX21 and acute myeloid leukemia.