TNF and psoriasis: In fact, by comparing skin lesions of immune-related psoriasis to anti-PD-1 with chronic plaque-type psoriasis and psoriasiform reactions to anti-TNF-α, we observed a prominent infiltrate of CD8+ T cells and CD11c+ DC, at levels and patterns of distribution of stable psoriasis, together with CD15+ neutrophils accumulating in sub corneal aggregates.