Finally, the analysis of selected innate immunity molecules showed that the type I IFN-β and the lymphotoxins LT-α and LT-β (belonging to the TNF cytokine family) mRNA are poorly expressed in psoriasis lesions induced by anti-PD-1, as compared to anti-TNF-α-induced psoriasis (Figure 4B). The gene discussed is PDCD1; the disease is psoriasis.