PCSK9 and psoriasis: Merleev et al. (2022) analyzed RNA-seq datasets including GSE121212, and they found that PCSK9 is a psoriasis susceptibility locus that is negatively related to IL36G; this result established a putative link between PCSK9 and inflammatory cytokine expression (Merleev et al., 2022). Furthermore, PCSK9 has been reported to be associated with inflammation in AD (Valenzuela et al., 2020).