These sets encompassed pathways such as breast cancer 5p15 amplicon, DNA metabolic process, reactome highly calcium permeable postsynaptic nicotinic acetylcholine receptors, EHMT2 targets up, reactome highly calcium permeable nicotinic acetylcholine receptors, regulation of xenophagy, PPARA pathway, PTEN pathway, RNA binding and genomic pathway. This evidence concerns the gene PTEN and breast cancer.