Laboratory tests showed leukopenia in 2 (10%) patients, anaemia in 15 (75%), low complement in 9 (45%), and elevated immunoglobulin in 5 (25%)0.19 patients (95%) were positive for antinuclear antibodies (ANAs), 11 (55%) for anti-SSA antibodies, 13 (65%) for anti-Ro52 antibodies, and 5 (25%) for Anti-dsDNA antibodies. This evidence concerns the gene TRIM21 and Decreased total leukocyte count.