PHLDA1 and neuroblastoma: To summarize our results, we can conclude that the presented experimental data broaden our knowledge on direct cytotoxicity of the ch14.18/CHO mAb on IMR-32 cells, its effects on changes of cellular proteome, extend our understanding of a role of PHLDA1 in signaling pathways regulating neuroblastoma cell fate in the studied model, and propose new protein candidates relevant to neuroblastoma biology for further studies.