Using the phospho-RTK protein array in the preliminary studies, we discovered that phosphorylation of EGFR is activated, while phosphorylation of IGF-1R is inhibited upon PHLDA1 downregulation in IMR-32 neuroblastoma cells transduced with a lentiviral PHLDA1-silencing vector as compared with control (Supplementary Figure S10). This evidence concerns the gene PHLDA1 and neuroblastoma.