Further analysis shows that the effect of COX7A1 on cell viability depends partly on the inhibition of autophagy [26]; and it was further revealed that overexpression of COX7A1 could enhance the activity of complex IV in TCA cycle and mitochondrial electron transport chain, thus increasing the sensitivity of lung cancer cells to ferroptosis induced by cysteine deprivation [26]. Here, COX7A1 is linked to lung carcinoma.