Finally, in our Immune Cohort, those GC patients with higher expression of COX7A1 had shorter OS and DFS (Additional file 5: Fig. S6); and COX7A1 in patients with TRG 2 or 3 was higher than that in patients with TRG 0 or 1 (P = 0.073, Wilcox. This evidence concerns the gene COX7A1 and gastric cancer.