It also has been suggested in some studies, that liver status e.g., the presence of cirrhosis [34] but also less severe liver damage may affect alcohol elimination [11]; however, results are rather conflicting which may also be related to the cause of liver disease e.g., chronic alcohol ingestion resulting in an induction of other ethanol metabolizing enzymes like CYP2E1 [35]. This evidence concerns the gene CYP2E1 and liver disorder.