, the authors analyzed the entire mitochondrial genome of blood samples from patients with tuberculosis to understand the mtDNA variants that may predispose the analyzed population to the disease, and observed a total of 83 variants in non-coding regions, in addition to two mutations with deleterious/damaging effects on MT-ND2 genes (m.4824G>A) and MT-ND6 (m.14180C>T)35. The gene discussed is MT-ND2; the disease is tuberculosis.