Patient 1 (P1) M/57Y was a chronic myeloid leukaemia (CML) patient with a novel in-frame BCR::ABL1 fusion transcript, habouring a breakpoint in BCR exon 23 (first 33 bp), an insertion of a 52 bp ABL1 pseudo-exon, to ABL1 exon 2 (NM_004327.4:r.-452_3759::uguugggauuacaggcgugagccaccacgaccggucaaauugcugucuuaua::NM_005157.6:r.80_*1992) (Fig. 6). Here, BCR is linked to chronic myelogenous leukemia, BCR-ABL1 positive.