It has been shown previously that platelets contribute to the recruitment of pericytes and cancer-associated fibroblasts in tumors and favor the epithelial-to-mesenchymal transition through the release of soluble factors like transforming growth factor beta (TGFβ) and platelet-derived growth factor B (PDGFB) from their secretion granules [2, 17, 46, 47]. This evidence concerns the gene PDGFB and cancer.