Strikingly, whereas tumor weight was negatively correlated with tumor granzyme B content in B16F1 tumors (Spearman’s rank correlation coefficient, rho = -0.7, p < 0.0001, n = 25), there was no association between tumor weight and granzyme B content in AT-3 tumors (Spearman’s rank correlation coefficient, rho = 0.118, p = 0.518, n = 32) (Fig. 1D), which were characterized by higher levels of programmed death-ligand 1 (PD-L1) (Fig. 1E). This evidence concerns the gene CD274 and neoplasm.